SCHEMBL30381811

CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CC(C)C)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	FOLH1	Q04609	6/20	0.46

▸	OPRM1	P35372	5/20	0.45

▸	OPRD1	P41143	5/20	0.45

▸	OPRK1	P41145	3/20	0.45

▸	KEAP1	Q14145	1/20	0.42

▸	GLO1	Q04760	1/20	0.41

▸	NMT2	O60551	1/20	0.41

▸	NMT1	P30419	1/20	0.41

▸	EGFR	P00533	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30317548	0.93	FOLH1 (0.46)	FOLH1OPRM1OPRD1OPRK1GLO1
SCHEMBL31194150	0.93	FOLH1 (0.49)	FOLH1OPRM1OPRD1OPRK1GLO1
SCHEMBL29360974	0.91	OPRM1 (0.46)	FOLH1OPRM1OPRD1OPRK1KEAP1
SCHEMBL30099535	0.90	FOLH1 (0.48)	FOLH1OPRM1OPRD1OPRK1GLO1
SCHEMBL29493327	0.89	OPRM1 (0.45)	OPRM1OPRD1OPRK1KEAP1EGFR
SCHEMBL29772133	0.88	FOLH1 (0.49)	FOLH1OPRM1OPRD1OPRK1KEAP1
SCHEMBL30320500	0.87	OPRM1 (0.43)	FOLH1OPRM1OPRD1OPRK1GLO1
SCHEMBL29771973	0.87	FOLH1 (0.44)	FOLH1OPRM1OPRD1OPRK1KEAP1
SCHEMBL29772029	0.87	OPRM1 (0.46)	FOLH1OPRM1OPRD1OPRK1KEAP1
SCHEMBL29599316	0.87	OPRM1 (0.51)	OPRM1OPRD1OPRK1NMT2NMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-110003337-B	IL17RA single domain antibody, nucleic acid and kit	深圳普瑞金生物药业股份有限公司	2023-05-09	—	—	CN	disclosed