Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29772039 | 0.95 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAGPR174THRB | |
| SCHEMBL29772052 | 0.94 | MAPT (0.55) | ALDH1A1MAPTLMNAGPR174THRB | |
| SCHEMBL29772057 | 0.90 | MAPT (0.56) | ALDH1A1MAPTLMNAGPR174THRB | |
| SCHEMBL10036407 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MAPTLMNAGPR174THRB | |
| SCHEMBL29772064 | 0.85 | HTR4 (0.42) | ALDH1A1MAPTLMNAGPR174SMN1; SMN2 | |
| SCHEMBL29772143 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAGPR174THRB | |
| SCHEMBL31334246 | 0.83 | MAPT (0.61) | ALDH1A1MAPTLMNAGPR174THRB | |
| SCHEMBL29772091 | 0.80 | L3MBTL1 (0.41) | ALDH1A1MAPTLMNAGPR174TDP1 | |
| SCHEMBL29772109 | 0.80 | MAPT (0.60) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL29772099 | 0.79 | L3MBTL1 (0.41) | ALDH1A1MAPTLMNAGPR174TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853846-A | Androgen receptor degradation agent and application thereof | 苏州国匡医药科技有限公司 | 2022-08-05 | — | — | CN | disclosed |