Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21633617 | 0.84 | LMNA (0.46) | ALDH1A1LMNAHTTKDM4EKMT2A | |
| SCHEMBL29772186 | 0.81 | KMT2A (0.43) | CNR2ALDH1A1LMNAMAPK1NPSR1 | |
| SCHEMBL31020216 | 0.78 | GAA (0.46) | ALDH1A1LMNAMAPK1NPSR1PKM | |
| SCHEMBL23496517 | 0.76 | BRD4 (0.46) | ALDH1A1LMNAMAPK1NPSR1KDM4E | |
| SCHEMBL21633644 | 0.76 | KDM4E (0.44) | ALDH1A1LMNAMAPK1NPSR1KDM4E | |
| SCHEMBL29772175 | 0.76 | HTR6 (0.46) | CNR2ALDH1A1LMNAMAPK1NPSR1 | |
| SCHEMBL15561085 | 0.73 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPK1NPSR1PKM | |
| SCHEMBL23042127 | 0.73 | HTR6 (0.49) | L3MBTL1 | |
| SCHEMBL21633719 | 0.71 | L3MBTL1 (0.42) | ALDH1A1NPSR1PKMHTTMAPT | |
| SCHEMBL12546712 | 0.70 | KMT2A (0.46) | ALDH1A1LMNAMAPK1NPSR1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021910-A1 | NEW THERAPEUTIC AGENTS FOR THE TREATMENT OF HAEMATOLOGICAL PATHOLOGIES | Universita' degli Studi di Palermo (IT) | 2022-07-06 | — | — | EP | disclosed |