Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.60 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.59 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.58 |
| ▸ | CCR4 | P51679 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2977236 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HTTHCRTR1HCRTR2AKR1C3 | |
| SCHEMBL2100430 | 0.96 | HCRTR1 (0.65) | ALDH1A1HTTHCRTR1HCRTR2AKR1C3 | |
| SCHEMBL30919357 | 0.96 | HCRTR1 (0.65) | ALDH1A1HTTHCRTR1HCRTR2AKR1C3 | |
| SCHEMBL2100435 | 0.96 | HCRTR1 (0.65) | ALDH1A1HTTHCRTR1HCRTR2AKR1C3 | |
| Hydrochloric Acid SCHEMBL10430459 | 0.95 | HCRTR1 (0.64) | ALDH1A1HTTHCRTR1HCRTR2AKR1C3 | |
| SCHEMBL1771231 | 0.86 | HCRTR1 (0.66) | HCRTR1HCRTR2AKR1C3CCR4MCOLN3 | |
| SCHEMBL1771060 | 0.86 | HCRTR1 (0.66) | HCRTR1HCRTR2AKR1C3CCR4MCOLN3 | |
| SCHEMBL1770402 | 0.85 | MMP1 (0.66) | HCRTR1HCRTR2CCR4MCOLN3TSHR | |
| SCHEMBL1770564 | 0.85 | MMP1 (0.66) | HCRTR1HCRTR2CCR4MCOLN3TSHR | |
| SCHEMBL2977278 | 0.84 | ALDH1A1 (0.72) | ALDH1A1HTTHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7777042-B2 | N-sulfonylpipecolic acid derivative FKBP binding composition and pharmaceutical use thereof | AVENTIS PHARMACEUTICALS INC. (US) | 2010-08-17 | — | — | US | claimed |
| US-20080139556-A1 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | AVENTIS PHARMACEUTICALS INC. (US) | 2008-06-12 | — | — | US | claimed |
| EP-1778637-A2 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | Aventis Pharmaceuticals, Inc. (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006012256-A2 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | AVENTIS PHARMACEUTICALS INC. (US) | 2006-02-02 | — | — | WO | claimed |
| US-7777042-B2 | N-sulfonylpipecolic acid derivative FKBP binding composition and pharmaceutical use thereof | AVENTIS PHARMACEUTICALS INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-20080139556-A1 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | AVENTIS PHARMACEUTICALS INC. (US) | 2008-06-12 | — | — | US | disclosed |
| EP-1778637-A2 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | Aventis Pharmaceuticals, Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006012256-A2 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | AVENTIS PHARMACEUTICALS INC. (US) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139556-A1 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | FKBP1A, FKBP1B, FKBP3 | ALDH1A1 3038/4885HTT 535/4885HCRTR1 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.