Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30254381 | 0.85 | CA12 (0.46) | FOLH1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL124096 | 0.83 | LMNA (0.55) | FOLH1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL31411079 | 0.81 | CA12 (0.39) | LMNACA12CA1CA2CA7 | |
| SCHEMBL8995261 | 0.80 | LMNA (0.48) | FOLH1LMNAKDM4EKMT2AALDH1A1 | |
| SCHEMBL2552794 | 0.77 | KMT2A (0.51) | FOLH1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL23640216 | 0.77 | MAOB (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10392101 | 0.77 | CLCN2 (0.40) | FOLH1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL25408142 | 0.76 | FOLH1 (0.50) | FOLH1LMNAKDM4EKMT2ACA12 | |
| SCHEMBL6840729 | 0.76 | KMT2A (0.51) | LMNAKDM4EKMT2AMEN1RECQL | |
| SCHEMBL31590625 | 0.76 | ALDH1A1 (0.54) | FOLH1LMNAKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954801-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114867727-B | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-114867727-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2022-08-05 | — | — | CN | disclosed |