Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 3/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28400037 | 0.92 | AGTR1 (0.41) | PCSK9AGTR1L3MBTL1HTR6CYP19A1 | |
| SCHEMBL29778010 | 0.92 | AGTR1 (0.41) | PCSK9AGTR1L3MBTL1HTR6CYP19A1 | |
| SCHEMBL28397417 | 0.92 | HTR6 (0.42) | PCSK9AGTR1L3MBTL1HTR6CYP19A1 | |
| SCHEMBL28402229 | 0.92 | PCSK9 (0.44) | PCSK9AGTR1L3MBTL1HTR6PSEN1 | |
| SCHEMBL28400704 | 0.88 | AGTR1 (0.39) | PCSK9AGTR1L3MBTL1HTR6CYP19A1 | |
| SCHEMBL29778020 | 0.88 | AGTR1 (0.39) | PCSK9AGTR1L3MBTL1HTR6CYP19A1 | |
| SCHEMBL28398527 | 0.88 | AGTR1 (0.45) | PCSK9AGTR1L3MBTL1HTR6CYP19A1 | |
| SCHEMBL28405785 | 0.87 | PCSK9 (0.45) | PCSK9AGTR1L3MBTL1HTR6CYP19A1 | |
| SCHEMBL28888940 | 0.87 | NOD1 (0.40) | PCSK9AGTR1HTR6PSEN1PSEN2 | |
| SCHEMBL29778012 | 0.86 | PCSK9 (0.44) | PCSK9AGTR1L3MBTL1HTR6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187298-B | C2-phosphono methylene indole compound and preparation method and application thereof | 成都大学 | 2022-07-19 | — | — | CN | disclosed |