Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21638079 | 1.00 | XDH (0.64) | XDHNPC1KDM4EMEN1POLB | |
| Asperpyrone A SCHEMBL29779212 | 0.82 | XDH (0.93) | XDHKDM4EMEN1POLBMAPT | |
| SCHEMBL29459738 | 0.81 | KDM4E (0.60) | XDHNPC1KDM4EMEN1POLB | |
| Fonsecinone A SCHEMBL29779161 | 0.78 | XDH (1.00) | XDHKDM4EMEN1POLBMAPT | |
| Aurasperone A SCHEMBL29779131 | 0.77 | XDH (0.80) | XDHPTGS1PTGS2ABCG2KLK7 | |
| Asperpyrone C SCHEMBL29779200 | 0.73 | XDH (0.73) | XDHPTGS1PTGS2ABCG2KLK7 | |
| SCHEMBL21638065 | 0.71 | NPC1 (1.00) | XDHNPC1KDM4EMEN1POLB | |
| SCHEMBL30780099 | 0.71 | NPC1 (1.00) | XDHNPC1KDM4EMEN1POLB | |
| SCHEMBL16226658 | 0.66 | ABCG2 (0.66) | XDHKDM4EMAPTPTGS1PTGS2 | |
| SCHEMBL29779211 | 0.66 | ABCG2 (0.66) | XDHKDM4EMAPTPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114848628-B | Application of naphtho gamma-pyrone compounds in preparation of anti-helicobacter pylori medicines or health care products | 暨南大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-114848628-A | Application of naphtho-gamma-pyrone compounds in preparation of anti-helicobacter pylori medicines or prevention health-care products | 暨南大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-113444644-B | Application of naphtho-gamma-pyrone compounds in preparation of anti-helicobacter pylori medicines or prevention health-care products | 暨南大学 | 2022-07-19 | — | — | CN | disclosed |