Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 1.00 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Asperpyrone A SCHEMBL29779212 | 0.96 | XDH (0.93) | XDHABCG2PTGS1PTGS2HIF1A | |
| Aurasperone A SCHEMBL29779131 | 0.89 | XDH (0.80) | XDHABCG2PTGS1PTGS2HIF1A | |
| Asperpyrone C SCHEMBL29779200 | 0.84 | XDH (0.73) | XDHABCG2PTGS1PTGS2HIF1A | |
| SCHEMBL29779211 | 0.80 | ABCG2 (0.66) | XDHABCG2PTGS1PTGS2HIF1A | |
| SCHEMBL16226658 | 0.80 | ABCG2 (0.66) | XDHABCG2PTGS1PTGS2HIF1A | |
| SCHEMBL21638079 | 0.78 | XDH (0.64) | XDHABCG2PTGS1PTGS2HIF1A | |
| SCHEMBL29779171 | 0.78 | XDH (0.64) | XDHABCG2PTGS1PTGS2HIF1A | |
| SCHEMBL15060671 | 0.75 | PTGS1 (0.59) | XDHABCG2PTGS1PTGS2KLK7 | |
| SCHEMBL15060672 | 0.72 | ABCG2 (0.67) | XDHABCG2PTGS1PTGS2HIF1A | |
| SCHEMBL8860175 | 0.71 | XDH (0.61) | XDHABCG2PTGS1PTGS2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118562908-A | Preparation method and application of benzopyrone compound in Kandelia candel endophytic fungi | 海南师范大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-114848628-B | Application of naphtho gamma-pyrone compounds in preparation of anti-helicobacter pylori medicines or health care products | 暨南大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-114848628-A | Application of naphtho-gamma-pyrone compounds in preparation of anti-helicobacter pylori medicines or prevention health-care products | 暨南大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-113444644-B | Application of naphtho-gamma-pyrone compounds in preparation of anti-helicobacter pylori medicines or prevention health-care products | 暨南大学 | 2022-07-19 | — | — | CN | disclosed |