Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | OXTR | P30559 | 2/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20777372 | 1.00 | GAA (0.54) | GAAMAPTTP53POLBNOTUM | |
| SCHEMBL20772763 | 0.86 | TRPM8 (0.54) | GAAMAPTTP53POLBMEN1 | |
| SCHEMBL20773041 | 0.85 | GAA (0.48) | GAAMAPTTP53POLBOXTR | |
| SCHEMBL20773840 | 0.84 | TP53 (0.52) | GAAMAPTTP53POLBMEN1 | |
| SCHEMBL22074451 | 0.84 | GAA (0.58) | GAAMAPTTP53POLBOXTR | |
| SCHEMBL20777304 | 0.83 | KMT2A (0.52) | GAAMAPTTP53MEN1KMT2A | |
| SCHEMBL20777355 | 0.83 | POLB (0.52) | GAAMAPTTP53POLBOXTR | |
| SCHEMBL10745005 | 0.78 | ALDH1A1 (0.55) | MAPTTP53POLBOXTRAVPR1A | |
| SCHEMBL22074382 | 0.77 | TRPM8 (0.63) | MAPTTP53POLBRAB9AALDH1A1 | |
| SCHEMBL22074352 | 0.72 | ALDH1A1 (0.48) | MAPTOXTRAVPR1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11434220-B2 | Use of physiological cooling active ingredients, and compositions comprising such active ingredients | BASF SE (DE) | 2022-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11434220-B2 | Use of physiological cooling active ingredients, and compositions comprising such active ingredients | TRPM8, TRPM7, TRPM5 | GAA 3218/4885MAPT 1475/4885TP53 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.