Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13555455 | 0.68 | PTGS2 (0.48) | NLRP3CYP2D6CYP2C9CYP2C19STAT3 | |
| SCHEMBL8513390 | 0.68 | PTGS2 (0.48) | NLRP3CYP2D6CYP2C9CYP2C19STAT3 | |
| SCHEMBL13555308 | 0.68 | PTGS2 (0.48) | NLRP3CYP2D6CYP2C9CYP2C19STAT3 | |
| Isoalantolactone SCHEMBL14029266 | 0.68 | NLRP3 (1.00) | NLRP3CYP2D6CYP2C9CYP2C19STAT3 | |
| Isoalantolactone SCHEMBL8223246 | 0.68 | NLRP3 (1.00) | NLRP3CYP2D6CYP2C9CYP2C19STAT3 | |
| Isoalantolactone SCHEMBL15944432 | 0.68 | NLRP3 (1.00) | NLRP3CYP2D6CYP2C9CYP2C19STAT3 | |
| Isoalantolactone SCHEMBL510111 | 0.68 | NLRP3 (1.00) | NLRP3CYP2D6CYP2C9CYP2C19STAT3 | |
| Alloalantolactone SCHEMBL29934802 | 0.67 | NLRP3 (0.50) | NLRP3CYP2D6CYP2C9CYP2C19STAT3 | |
| Alloalantolactone SCHEMBL30105635 | 0.67 | NLRP3 (0.50) | NLRP3CYP2D6CYP2C9CYP2C19STAT3 | |
| Peruvin SCHEMBL29412594 | 0.65 | PAX8 (0.52) | NLRP3CYP2D6CYP2C9CYP2C19STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119925344-A | Application of telalactone in preparing medicament for inhibiting tumor angiogenesis | 山东大学 | 2025-05-06 | — | — | CN | disclosed |
| CN-112263600-B | Carpesium abrotanoides extract, preparation method and application thereof in anti-liver cancer active drugs passing through JAK2/STAT3 channel | 湖南省中医药研究院 | 2022-07-05 | — | — | CN | disclosed |