Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alloalantolactone SCHEMBL30105635 | 1.00 | NLRP3 (0.50) | NLRP3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28250594 | 0.73 | PKM (0.41) | NLRP3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL531268 | 0.73 | PKM (0.41) | NLRP3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14987814 | 0.73 | PKM (0.41) | NLRP3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14987851 | 0.73 | PKM (0.41) | NLRP3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL530805 | 0.68 | NLRP3 (0.36) | NLRP3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8513390 | 0.67 | PTGS2 (0.48) | NLRP3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13555455 | 0.67 | PTGS2 (0.48) | NLRP3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13555308 | 0.67 | PTGS2 (0.48) | NLRP3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Isoalantolactone SCHEMBL15944432 | 0.67 | NLRP3 (1.00) | NLRP3CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220291237-A1 | Gene Expression Inflammatory Age and Its Uses | Edifice Health, Inc. (US) | 2022-09-15 | — | — | US | disclosed |