Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27813370 | 0.93 | P2RX1 (0.51) | P2RX1HTTNPC1RAB9ALCK | |
| SCHEMBL297830 | 0.90 | KDM4E (0.43) | P2RX1HTTNPC1RAB9APOLB | |
| SCHEMBL299472 | 0.85 | LMNA (0.47) | P2RX1NPC1RAB9APOLBHPGD | |
| SCHEMBL29409938 | 0.84 | KCNK3 (0.59) | HTTNPC1RAB9APOLBHPGD | |
| SCHEMBL12570375 | 0.84 | KCNK3 (0.59) | HTTNPC1RAB9APOLBHPGD | |
| SCHEMBL1275530 | 0.83 | ALDH1A1 (0.44) | HTTNPC1RAB9AKMT2AMAPT | |
| SCHEMBL699720 | 0.82 | PKM (0.48) | P2RX1HTTRAB9AGAAKCNJ11 | |
| SCHEMBL16863615 | 0.81 | KCNK3 (0.55) | HTTNPC1RAB9APOLBHPGD | |
| SCHEMBL21620295 | 0.81 | KCNJ11 (0.49) | HTTNPC1RAB9AHPGDGAA | |
| SCHEMBL699354 | 0.81 | ITGB3 (0.42) | P2RX1HTTRAB9AGAAKCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427427-A1 | 4 -CYANO- 3 -BENZOYLAMINO-N- PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | Syngenta Participations AG (CH) | 2012-03-14 | — | — | EP | disclosed |