Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ11 | Q14654 | 9/20 | 0.46 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297830 | 0.87 | KDM4E (0.43) | KCNJ11TRPA1CYP1A2KDM4EALDH1A1 | |
| SCHEMBL289387 | 0.80 | KCNJ11 (0.36) | KCNJ11ABCC9ABCC8KCNJ8KDM4E | |
| SCHEMBL1275497 | 0.80 | MLYCD (0.51) | KCNJ11ABCC9ABCC8KCNJ8KDM4E | |
| SCHEMBL1823437 | 0.78 | ABCC9 (0.57) | KCNJ11ABCC9ABCC8KCNJ8CYP1A2 | |
| SCHEMBL3709143 | 0.77 | MAPT (0.43) | KCNJ11ABCC9ABCC8KCNJ8CYP1A2 | |
| SCHEMBL299219 | 0.76 | P2RX1 (0.48) | KCNJ11CYP1A2KDM4EALDH1A1MAPT | |
| SCHEMBL2103913 | 0.76 | KCNK3 (0.57) | KCNJ11ABCC9ABCC8KCNJ8MAPT | |
| SCHEMBL13129140 | 0.76 | KDM4E (0.50) | CYP1A2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL1275245 | 0.75 | KCNK3 (0.50) | KCNJ11ABCC9ABCC8KCNJ8KDM4E | |
| SCHEMBL1275206 | 0.75 | MAPT (0.39) | TRPA1KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427427-A1 | 4 -CYANO- 3 -BENZOYLAMINO-N- PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | Syngenta Participations AG (CH) | 2012-03-14 | — | — | EP | disclosed |