SCHEMBL2978597

SCHEMBL2978597

O=C(O)[C@H](CS)NCCc1ccc(O)cc1O

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ TYR P14679 5/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2993116 0.99 MEN1 (0.47) MEN1KMT2ATYR
SCHEMBL2985265 0.89 EGFR (0.43) MEN1KMT2A
SCHEMBL2980769 0.87 MEN1 (0.49) MEN1KMT2ATYR
SCHEMBL2993112 0.86 TYR (0.45) MEN1KMT2ATYR
SCHEMBL2982723 0.83 MEN1 (0.46) MEN1KMT2ATYR
SCHEMBL2982928 0.82 MPO (0.46) —
SCHEMBL2980636 0.82 ALOX5 (0.48) MEN1KMT2ATYR
SCHEMBL2979325 0.81 ALOX5 (0.47) MEN1KMT2ATYR
SCHEMBL2987290 0.81 PTGS1 (0.51) MEN1KMT2A
SCHEMBL2990315 0.80 MEN1 (0.46) MEN1KMT2ATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents BIODERM RESEARCH (US) 2009-03-19 — — US claimed
US-7777073-B2 Topical delivery system for antiaging and skin whitening agents BIODERM RESEARCH (US) 2010-08-17 — — US disclosed
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents BIODERM RESEARCH (US) 2009-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents TYR, MMP17, MMP1 MEN1 4836/4885KMT2A 2383/4885TYR 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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