Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23124130 | 1.00 | CDK5 (0.48) | CDK5CDK5R1KDM4CKDM5BLMNA | |
| SCHEMBL4840104 | 0.81 | HPGDS (0.58) | CDK5CDK5R1KDM4CKDM5BLMNA | |
| SCHEMBL29786346 | 0.80 | KDM4C (0.48) | CDK5CDK5R1KDM4CKDM5BHSP90AA1 | |
| SCHEMBL23123907 | 0.80 | KDM4C (0.48) | CDK5CDK5R1KDM4CKDM5BHSP90AA1 | |
| SCHEMBL5761329 | 0.79 | CYP11B1 (0.54) | CDK5CDK5R1KDM4CKDM5BLMNA | |
| SCHEMBL5755079 | 0.79 | NPC1 (0.60) | CDK5CDK5R1LMNAMEN1KMT2A | |
| SCHEMBL7510401 | 0.78 | CDK5 (0.50) | CDK5CDK5R1KDM4CKDM5BLMNA | |
| SCHEMBL23123527 | 0.76 | HTR1A (0.43) | CDK5CDK5R1KDM4CKDM5BMEN1 | |
| SCHEMBL23123924 | 0.76 | DRD2 (0.44) | CDK5CDK5R1KDM4CKDM5B | |
| SCHEMBL5757721 | 0.75 | CLK1 (0.50) | CDK5CDK5R1KDM4CKDM5BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787135-A | Substituted imidazole carboxamides and their use in the treatment of medical disorders | 比亚尔R&D投资股份公司 | 2022-07-22 | — | — | CN | disclosed |