Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454821 | 0.85 | LMNA (0.34) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL30970938 | 0.84 | PDE4A (0.43) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL706623 | 0.82 | ACLY (0.33) | ACLY | |
| SCHEMBL988316 | 0.81 | PDE4A (0.41) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL6889487 | 0.79 | PDE4A (0.39) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL29003669 | 0.77 | PDE4A (0.37) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL6533666 | 0.76 | ACLY (0.32) | ACLY | |
| SCHEMBL3430764 | 0.76 | ACLY (0.32) | ACLY | |
| SCHEMBL30234257 | 0.76 | PDE4A (0.43) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL28064686 | 0.76 | PDE4A (0.43) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215886-B | Compounds and compositions as endosomal Toll-like receptor inhibitors | 诺华股份有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-109641899-B | Compounds and compositions as endosomal Toll-like receptor inhibitors | 诺华股份有限公司 | 2022-07-22 | — | — | CN | disclosed |