Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27181873 | 1.00 | ACLY (0.32) | ACLYACACBACACAHSPD1BLM | |
| SCHEMBL3430764 | 1.00 | ACLY (0.32) | ACLYACACBACACAHSPD1BLM | |
| SCHEMBL706623 | 0.94 | ACLY (0.33) | ACLYACACBACACAHSPD1BLM | |
| SCHEMBL29786808 | 0.76 | PDE4A (0.41) | ACLY | |
| SCHEMBL17889062 | 0.70 | PDE4A (0.55) | PTPN1 | |
| SCHEMBL5168154 | 0.70 | PDE4A (0.55) | PTPN1 | |
| SCHEMBL436281 | 0.70 | PDE4A (0.55) | PTPN1 | |
| SCHEMBL28380507 | 0.70 | PDE4A (0.55) | PTPN1 | |
| SCHEMBL28496980 | 0.70 | PDE4A (0.55) | PTPN1 | |
| SCHEMBL28465166 | 0.68 | PDE4A (0.53) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6893648-B2 | Composition and method for treatment of vaginal dryness | MERMELSTEIN HAROLD (US) | 2005-05-17 | — | — | US | claimed |
| US-20030170325-A1 | Composition and method for treatment of vaginal dryness | MERMELSTEIN HAROLD (US) | 2003-09-11 | — | — | US | claimed |
| US-6893648-B2 | Composition and method for treatment of vaginal dryness | MERMELSTEIN HAROLD (US) | 2005-05-17 | — | — | US | disclosed |
| US-20030170325-A1 | Composition and method for treatment of vaginal dryness | MERMELSTEIN HAROLD (US) | 2003-09-11 | — | — | US | disclosed |