Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | OXTR | P30559 | 3/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.44 |
| ▸ | ASPH | Q12797 | 1/20 | 0.44 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2040123 | 1.00 | ATR (0.49) | ATRP4HTMKDM4EALDH1A1HPGD | |
| SCHEMBL27755250 | 0.80 | EGLN1 (0.59) | P4HTMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL22445719 | 0.79 | LDHA (0.57) | ATRP4HTMKDM4EALDH1A1HPGD | |
| SCHEMBL5934219 | 0.76 | ALPL (0.49) | ATRP4HTMKDM4EALDH1A1HPGD | |
| SCHEMBL29685241 | 0.76 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL11908982 | 0.74 | ATR (0.74) | ATR | |
| SCHEMBL2644580 | 0.74 | ALOX5AP (0.68) | HSD17B10METAP2ALOX5APFEN1 | |
| SCHEMBL4214978 | 0.74 | ALOX15 (0.51) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL22717860 | 0.73 | KDM4E (0.54) | P4HTMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2929188 | 0.73 | LDHA (0.56) | P4HTMKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773249-B | Compounds, pharmaceutical compositions and methods for treating inflammatory diseases | 艾匹克治疗公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-114773249-A | Compounds, pharmaceutical compositions and methods for treating inflammatory diseases | 艾匹克治疗公司 | 2022-07-22 | — | — | CN | disclosed |