Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29788091 | 0.87 | FFAR2 (0.51) | KDM4EALDH1A1HPGDMAOASMN1; SMN2 | |
| SCHEMBL2040639 | 0.87 | FFAR2 (0.51) | KDM4EALDH1A1HPGDMAOASMN1; SMN2 | |
| SCHEMBL99181 | 0.85 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDMAOASMN1; SMN2 | |
| SCHEMBL13053955 | 0.83 | NPC1 (0.62) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL16429258 | 0.83 | MAOA (0.57) | KDM4EALDH1A1HPGDMAOANPC1 | |
| SCHEMBL29116511 | 0.83 | MAOA (0.61) | KDM4EALDH1A1HPGDMAOASMN1; SMN2 | |
| SCHEMBL6326391 | 0.83 | MAOA (0.53) | KDM4EALDH1A1HPGDMAOASMN1; SMN2 | |
| SCHEMBL28943565 | 0.81 | HDAC1 (0.54) | KDM4EALDH1A1HPGDMAOASMN1; SMN2 | |
| SCHEMBL14817806 | 0.81 | ALDH1A1 (0.65) | KDM4EALDH1A1HPGDMAOASMN1; SMN2 | |
| SCHEMBL29375325 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDMAOASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773249-A | Compounds, pharmaceutical compositions and methods for treating inflammatory diseases | 艾匹克治疗公司 | 2022-07-22 | — | — | CN | disclosed |