SCHEMBL297883

SCHEMBL297883

Cc1ccc([Si](Cl)(Cl)c2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 4/20 0.38
CA2 P00918 2/20 0.38
CA1 P00915 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
TSHR P16473 3/20 0.35
LMNA P02545 2/20 0.35
ALOX12 P18054 1/20 0.35
CYP2A6 P11509 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
IDO1 P14902 1/20 0.33
CCR1 P32246 1/20 0.33
CCR5 P51681 1/20 0.33
CCR8 P51685 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482589 0.89 ACHE (0.48) ACHETDP1ALDH1A1TSHRLMNA
SCHEMBL301896 0.81 ACHE (0.50) ACHETDP1ALDH1A1CA2CA1
SCHEMBL1538600 0.81 ACHE (0.50) ACHETDP1ALDH1A1CA2CA1
Toluene SCHEMBL28546934 0.80 ACHE (0.58) ACHETDP1ALDH1A1TSHRLMNA
SCHEMBL5034146 0.79 ACHE (0.47) ACHETDP1ALDH1A1CA2CA1
SCHEMBL80628 0.79 ACHE (0.47) ACHETDP1ALDH1A1CA2CA1
SCHEMBL1798922 0.79 ACHE (0.47) ACHETDP1ALDH1A1CA2CA1
SCHEMBL1538886 0.77 ACHE (0.44) ACHETDP1ALDH1A1CA2CA1
SCHEMBL1538642 0.77 ACHE (0.44) ACHETDP1ALDH1A1CA2CA1
SCHEMBL12817069 0.75 TDP1 (0.42) ACHETDP1ALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117596783-B High-frequency carbon-hydrogen copper-clad plate and preparation method thereof 江苏耀鸿电子有限公司 2024-10-01 CN claimed
CN-118638146-A Preparation method of chlorosilane amine compound 中化学科学技术研究有限公司 2024-09-13 CN claimed
CN-118308883-A Preparation process of shading anti-radiation silver-coated roller shutter 江阴五岳建筑节能科技有限公司 2024-07-09 CN claimed
CN-112652756-B In-situ polymerization protection lithium metal electrode 通用汽车环球科技运作有限责任公司 2024-05-24 CN claimed
CN-117596783-A High-frequency carbon-hydrogen copper-clad plate and preparation method thereof 江苏耀鸿电子有限公司 2024-02-23 CN claimed
US-11515538-B2 In-situ polymerization to protect lithium metal electrodes GM Global Technology Operations LLC (US) 2022-11-29 US claimed
EP-2287231-B1 Ulltraviolet transmissive polyhedral silsesquioxane polymers PANASONIC CORP (JP) 2012-06-06 EP claimed
US-20110251357-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS PANASONIC ELECTRIC WORKS CO., LTD. 2011-10-13 US claimed
EP-2287231-A2 Ulltraviolet transmissive polyhedral silesquioxane polymers Panasonic Electric Works Co., Ltd. (JP) 2011-02-23 EP claimed
JP-2008523165-A 2008-07-03 JP claimed
EP-1833880-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS Matsushita Electric Works, Ltd. (JP) 2007-09-19 EP claimed
WO-2006062219-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2006-06-15 WO claimed
US-20060122351-A1 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2006-06-08 US claimed
EP-0447066-B2 Pneumatic tyres BRIDGESTONE CORP (JP) 2000-08-16 EP claimed
US-5409969-A Comprising silica filler, carbon black, silane coupler, living polymer of butadiene-styrene BRIDGESTONE CORPORATION (JP) 1995-04-25 US claimed
EP-0447066-A1 Pneumatic tyres Bridgestone Corporation (JP) 1991-09-18 EP claimed
US-5017636-A Also containing polyisoprene, natural rubber, butadiene-styrene copolymer, wear and heat resistance, resilience JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-21 US claimed
JP-62227908-A None JP disclosed
US-4577039-A Method of preparing hexamethylcyclotrisilazane PETRARCH SYSTEMS INC. (US) 1986-03-18 US disclosed
US-4405589-A ALKYL OR ARYL SILICON CHLORIDES, AMMONIA, ROASTING UBE INDUSTRIES, LTD. (JP) 1983-09-20 US disclosed