SCHEMBL3482589

SCHEMBL3482589

Cc1ccc([Si](Cl)(Cl)c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.48
LMNA P02545 2/20 0.48
TSHR P16473 1/20 0.48
ALOX12 P18054 1/20 0.48
HPGD P15428 3/20 0.41
TDP1 Q9NUW8 3/20 0.40
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 2/20 0.39
NPC1 O15118 6/20 0.39
RAB9A P51151 6/20 0.39
POLB P06746 2/20 0.39
NFKB1 P19838 2/20 0.39
NFKB2 Q00653 2/20 0.39
RELA Q04206 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ESR1 P03372 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL28546934 0.92 ACHE (0.58) ACHELMNATSHRALOX12HPGD
SCHEMBL297883 0.89 ACHE (0.50) ACHELMNATSHRALOX12TDP1
SCHEMBL705847 0.87 ESR1 (0.40) ACHELMNATSHRALOX12TDP1
SCHEMBL12816296 0.85 LMNA (0.48) ACHELMNATSHRALOX12HPGD
SCHEMBL3481733 0.85 LMNA (0.48) ACHELMNATSHRALOX12HPGD
SCHEMBL76000 0.84 TSHR (0.39) ACHELMNATSHRALOX12TDP1
SCHEMBL29120692 0.84 TSHR (0.39) ACHELMNATSHRALOX12TDP1
SCHEMBL10319854 0.83 ACHE (0.46) ACHELMNATSHRALOX12HPGD
SCHEMBL3481779 0.81 ACHE (0.38) ACHELMNATSHRALOX12HPGD
Fluoride SCHEMBL5604818 0.81 TSHR (0.37) ACHELMNATSHRALOX12TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4142333-A None JP disclosed
EP-3782599-B1 DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES VOCO GMBH (DE) 2025-09-17 EP disclosed
US-11992538-B2 Polymerizable dental composition based on condensed silanes VOCO GMBH (DE) 2024-05-28 US disclosed
US-20210052469-A1 POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES VOCO GMBH (DE) 2021-02-25 US disclosed
EP-3782599-A1 DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES VOCO GmbH (DE) 2021-02-24 EP disclosed
EP-2128897-B1 SILICON DIELECTRIC TREATING AGENT FOR USE AFTER ETCHING, PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE FUJITSU LTD (JP) 2015-05-06 EP disclosed
CN-102898655-B Method for preparing optically active polysilane UNIV HANGZHOU NORMAL 2014-06-25 CN disclosed
US-8716209-B2 Agent for post-etch treatment of silicon dielectric film, method of manufacturing semiconductor device, and semiconductor device FUJITSU LIMITED (JP) 2014-05-06 US disclosed
CN-102898655-A Method for preparing optically active polysilane UNIV HANGZHOU NORMAL 2013-01-30 CN disclosed
US-20100007031-A1 AGENT FOR POST-ETCH TREATMENT OF SILICON DIELECTRIC FILM, METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2010-01-14 US disclosed
EP-2128897-A1 SILICON DIELECTRIC TREATING AGENT FOR USE AFTER ETCHING, PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE Fujitsu Limited (JP) 2009-12-02 EP disclosed
JP-H04142333-A POLY(((4-ALKYLPHENYL)PHENYLSILANE) AND ITS PRODUCTION TOAGOSEI CHEM IND CO LTD 1992-05-15 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11992538-B2 Polymerizable dental composition based on condensed silanes NCAPH, RCC1, NCAPD2 ACHE 3835/4885LMNA 322/4885TSHR 4596/4885
US-20210052469-A1 POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES NCAPH, RCC1, NCAPD2 ACHE 3835/4885LMNA 322/4885TSHR 4596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.