Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMPD2 | Q01433 | 13/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23124060 | 1.00 | AMPD2 (0.46) | AMPD2HSD11B1LMNAADRA2ASIGMAR1 | |
| SCHEMBL30128700 | 0.86 | SMN1; SMN2 (0.42) | AMPD2HSD11B1LMNASIGMAR1CNR2 | |
| SCHEMBL9073520 | 0.81 | AMPD2 (0.49) | AMPD2LMNA | |
| SCHEMBL29789663 | 0.80 | AMPD2 (0.51) | AMPD2LMNASIGMAR1 | |
| SCHEMBL23124104 | 0.80 | AMPD2 (0.51) | AMPD2LMNASIGMAR1 | |
| SCHEMBL11835343 | 0.75 | DRD2 (0.45) | AMPD2SIGMAR1 | |
| SCHEMBL11786097 | 0.72 | DRD2 (0.58) | AMPD2LMNASIGMAR1 | |
| SCHEMBL11783262 | 0.72 | AMPD2 (0.50) | AMPD2LMNAMEN1KMT2A | |
| SCHEMBL23123417 | 0.71 | P2RX4 (0.44) | LMNACNR2 | |
| SCHEMBL29789660 | 0.71 | P2RX4 (0.44) | LMNACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901652-A | Substituted saturated and unsaturated N-heterocyclic carboxamides and related compounds for the treatment of medical disorders | 比亚尔R&D投资股份公司 | 2022-08-12 | — | — | CN | disclosed |
| EP-4031540-A1 | SUBSTITUTED, SATURATED AND UNSATURATED N-HETEROCYCLIC CARBOXAMIDES AND RELATED COMPOUNDS FOR THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | Bial-R&D Investments, S.A. (PT) | 2022-07-27 | — | — | EP | disclosed |