Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.58 |
| ▸ | DRD4 | P21917 | 7/20 | 0.58 |
| ▸ | AMPD2 | Q01433 | 6/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9073520 | 0.90 | AMPD2 (0.49) | DRD2DRD4AMPD2CRHBPCRHR2 | |
| SCHEMBL11783262 | 0.89 | AMPD2 (0.50) | DRD2DRD4AMPD2CRHBPCRHR2 | |
| SCHEMBL11835343 | 0.85 | DRD2 (0.45) | DRD2DRD4AMPD2CRHBPCRHR2 | |
| SCHEMBL11783355 | 0.84 | DRD2 (0.46) | DRD2DRD4AMPD2TP53SIGMAR1 | |
| SCHEMBL11834803 | 0.83 | DRD2 (0.43) | DRD2DRD4AMPD2CRHBPCRHR2 | |
| SCHEMBL11675982 | 0.83 | DRD2 (0.48) | DRD2DRD4AMPD2CRHBPCRHR2 | |
| SCHEMBL11784227 | 0.82 | AMPD2 (0.51) | DRD2DRD4AMPD2CRHBPCRHR2 | |
| SCHEMBL9155272 | 0.81 | CRHBP (0.48) | DRD2DRD4CRHBPCRHR2LMNA | |
| SCHEMBL11680703 | 0.80 | DRD2 (0.45) | DRD2DRD4SIGMAR1LMNA | |
| SCHEMBL11428861 | 0.80 | CRHBP (0.45) | DRD2DRD4CRHBPCRHR2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000141-A | SUBSTITUTED TETRAHYDRO QUINOLINE CATIONIC DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |
| US-3991042-A | Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-09 | — | — | US | disclosed |