Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | AMPD2 | Q01433 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11834803 | 0.88 | DRD2 (0.43) | DRD2DRD4CRHBPCRHR2AMPD2 | |
| SCHEMBL9073520 | 0.86 | AMPD2 (0.49) | DRD2DRD4ALOX12CRHBPCRHR2 | |
| SCHEMBL11786097 | 0.85 | DRD2 (0.58) | DRD2DRD4SIGMAR1CRHBPCRHR2 | |
| SCHEMBL11783262 | 0.85 | AMPD2 (0.50) | DRD2DRD4CRHBPCRHR2AMPD2 | |
| SCHEMBL11782496 | 0.85 | SIGMAR1 (0.45) | DRD2DRD4SIGMAR1HRH2CACNA1G | |
| SCHEMBL11679771 | 0.82 | RAB9A (0.41) | DRD2CRHBPCRHR2 | |
| SCHEMBL9155272 | 0.77 | CRHBP (0.48) | DRD2DRD4CRHBPCRHR2 | |
| SCHEMBL11428861 | 0.76 | CRHBP (0.45) | DRD2DRD4SIGMAR1CRHBPCRHR2 | |
| SCHEMBL11784227 | 0.76 | AMPD2 (0.51) | DRD2DRD4SIGMAR1CRHBPCRHR2 | |
| SCHEMBL11419193 | 0.76 | GAA (0.49) | DRD2DRD4L3MBTL1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000141-A | SUBSTITUTED TETRAHYDRO QUINOLINE CATIONIC DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |