Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2990220 | 0.84 | OPRM1 (0.44) | OPRL1OPRM1 | |
| SCHEMBL2985450 | 0.82 | OPRM1 (0.47) | OPRL1OPRM1 | |
| SCHEMBL4850386 | 0.79 | OPRL1 (0.74) | OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL4850777 | 0.78 | OPRL1 (0.77) | OPRL1OPRM1 | |
| SCHEMBL2974572 | 0.77 | OPRM1 (0.64) | OPRL1OPRM1 | |
| SCHEMBL3409995 | 0.77 | OPRM1 (0.50) | OPRL1OPRM1 | |
| SCHEMBL2978912 | 0.76 | OPRM1 (0.54) | OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL2976610 | 0.76 | OPRM1 (0.66) | OPRL1OPRM1 | |
| SCHEMBL2983437 | 0.75 | OPRM1 (0.58) | OPRL1OPRM1 | |
| SCHEMBL2981453 | 0.75 | RAB9A (0.39) | OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786328-B2 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2010-08-31 | — | — | US | claimed |
| US-20070281954-A1 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-12-06 | — | — | US | claimed |
| US-7786328-B2 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2010-08-31 | — | — | US | disclosed |
| US-20070281954-A1 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281954-A1 | Cyclohexyl-1,4-diamine compounds | DPYD, PKD1, AOC1 | OPRL1 1292/4885OPRM1 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.