Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CTSC | P53634 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | VHL | P40337 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29484185 | 0.98 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CTSCCMA1F2 | |
| SCHEMBL31609177 | 0.94 | REN (0.53) | CMA1RENACESLC6A2 | |
| SCHEMBL6880524 | 0.89 | CTRB1 (0.48) | ALDH1A1HSD17B10CTSCCMA1F2 | |
| SCHEMBL6878588 | 0.89 | CTRB1 (0.48) | ALDH1A1HSD17B10CTSCCMA1F2 | |
| SCHEMBL14906464 | 0.89 | CTRB1 (0.48) | ALDH1A1HSD17B10CTSCCMA1F2 | |
| SCHEMBL14906471 | 0.89 | CTRB1 (0.48) | ALDH1A1HSD17B10CTSCCMA1F2 | |
| SCHEMBL6876472 | 0.89 | CTRB1 (0.48) | ALDH1A1HSD17B10CTSCCMA1F2 | |
| SCHEMBL6876603 | 0.89 | CTRB1 (0.48) | ALDH1A1HSD17B10CTSCCMA1F2 | |
| SCHEMBL31190175 | 0.89 | BDKRB2 (0.46) | ALDH1A1HSD17B10CTSCCMA1F2 | |
| SCHEMBL30630986 | 0.88 | REN (0.56) | CTSCCMA1RENACESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002907-A1 | STABLE CORONAVIRUS PROTEINS AND VACCINE COMPOSITIONS THEREOF | UNIVERSITY OF WASHINGTON | 2025-01-02 | — | — | US | disclosed |
| US-12129465-B2 | Stable coronavirus proteins and vaccine compositions thereof | UNIVERSITY OF WASHINGTON (US) | 2024-10-29 | — | — | US | disclosed |
| US-20240277831-A1 | POLYPEPTIDES, COMPOSITIONS, AND THEIR USE TO TREAT OR LIMIT DEVELOPMENT OF AN INFECTION | UNIVERSITY OF WASHINGTON | 2024-08-22 | — | — | US | disclosed |
| EP-4271698-A1 | STABLE CORONAVIRUS PROTEINS AND VACCINE COMPOSITIONS THEREOF | University of Washington (US) | 2023-11-08 | — | — | EP | disclosed |
| CN-116761624-A | Stabilized coronavirus proteins and vaccine compositions thereof | 华盛顿大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-116096404-A | Polypeptides, compositions and use thereof for treating or limiting the progression of infections | 华盛顿大学 | 2023-05-09 | — | — | CN | disclosed |
| US-20220325279-A1 | STABLE CORONAVIRUS PROTEINS AND VACCINE COMPOSITIONS THEREOF | UNIVERSITY OF WASHINGTON (US) | 2022-10-13 | — | — | US | disclosed |
| WO-2022146484-A1 | STABLE CORONAVIRUS PROTEINS AND VACCINE COMPOSITIONS THEREOF | UNIVERSITY OF WASHINGTON (US) | 2022-07-07 | — | — | WO | disclosed |