SCHEMBL2979192

SCHEMBL2979192

CNC(=O)CN(C(=O)O)C1CCN(CCc2cccc(C(F)(F)F)c2)CC1

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DCUN1D1 Q96GG9 13/20 0.59
UBE2M P61081 12/20 0.59
CARM1 Q86X55 1/20 0.53
PRMT6 Q96LA8 1/20 0.53
OPRM1 P35372 2/20 0.50
SIGMAR1 Q99720 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2979356 0.82 OPRM1 (0.52) OPRM1
SCHEMBL2969726 0.80 OPRM1 (0.57) OPRM1
SCHEMBL2973367 0.79 OPRM1 (0.58) OPRM1
SCHEMBL4702695 0.78 KMT2A (0.53) CARM1PRMT6OPRM1SIGMAR1
SCHEMBL3605490 0.78 SIGMAR1 (0.64) DCUN1D1UBE2MCARM1PRMT6SIGMAR1
SCHEMBL2967729 0.76 OPRM1 (0.50) DCUN1D1OPRM1
SCHEMBL2967235 0.76 OPRM1 (0.48) OPRM1SIGMAR1
SCHEMBL18640224 0.74 DCUN1D1 (1.00) DCUN1D1UBE2M
SCHEMBL23077897 0.74 DCUN1D1 (0.72) DCUN1D1UBE2MOPRM1
SCHEMBL18640253 0.74 DCUN1D1 (1.00) DCUN1D1UBE2M

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7781590-B2 Piperidinylalkylcarbamate derivatives, methods for their preparation and the therapeutic use thereof as fatty acid amido hydrolase enzyme inhibitors SANOFI-AVENTIS (FR) 2010-08-24 US disclosed
US-20070021403-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS SANOFI-AVENTIS (FR) 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070021403-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS FAAH, FAAH2, CNR2 DCUN1D1 4751/4885UBE2M 3836/4885CARM1 3929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.