SCHEMBL547722

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL548288	0.87	MEN1 (0.39)	MEN1KMT2AHSP90AA1CA12CA4
	SCHEMBL548149	0.83	MEN1 (0.42)	MEN1KMT2AHSP90AA1ABCB1CA12
	SCHEMBL548717	0.82	MEN1 (0.45)	MEN1KMT2AHSP90AA1ABCB1CA12
	SCHEMBL548670	0.78	PTPN1 (0.39)	MEN1KMT2AHSP90AA1ABCB1CA12
	SCHEMBL29793488	0.78	PTPN1 (0.39)	MEN1KMT2AHSP90AA1ABCB1CA12
	SCHEMBL548577	0.76	ALDH1A1 (0.36)	MEN1KMT2AHSP90AA1CYP3A4MAPT
	SCHEMBL547866	0.72	CA1 (0.39)	MEN1KMT2AHSP90AA1MAOBCYP3A4
	SCHEMBL548159	0.69	HNF4A (0.46)	MEN1KMT2AALDH1A1RAB9AALOX15
	SCHEMBL547708	0.69	MEN1 (0.41)	MEN1KMT2AHSP90AA1ABCB1CA12
	SCHEMBL28715775	0.66	PTPN1 (0.55)	FTOALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.