SCHEMBL29794834

SCHEMBL29794834

CS(=O)(=O)Nc1cccc(N)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.61
KEAP1 Q14145 1/20 0.57
ALDH1A1 P00352 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
TYRO3 Q06418 1/20 0.55
POLB P06746 2/20 0.53
DDX3X O00571 1/20 0.50
KIF11 P52732 1/20 0.49
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
GFER P55789 1/20 0.48
KMT2A Q03164 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
KDM1A O60341 1/20 0.48
NR3C1 P04150 1/20 0.47
BRD4 O60885 1/20 0.46
HSD17B1 P14061 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL399855 1.00 HTR6 (0.61) HTR6KEAP1ALDH1A1SMN1; SMN2TYRO3
SCHEMBL698855 0.85 KEAP1 (0.70) KEAP1ALDH1A1SMN1; SMN2POLBKIF11
SCHEMBL10138631 0.85 HTR6 (0.57) HTR6ALDH1A1SMN1; SMN2TYRO3POLB
SCHEMBL8547020 0.82 HTR6 (0.62) HTR6ALDH1A1POLBDDX3XKDM4E
SCHEMBL11655851 0.81 HTR6 (0.57) HTR6ALDH1A1SMN1; SMN2POLBDDX3X
SCHEMBL12728616 0.80 HTR6 (0.61) HTR6ALDH1A1SMN1; SMN2POLBDDX3X
SCHEMBL27861796 0.80 HTR6 (0.61) HTR6ALDH1A1SMN1; SMN2POLBDDX3X
SCHEMBL16181301 0.80 HTR6 (0.51) HTR6ALDH1A1SMN1; SMN2TYRO3POLB
SCHEMBL31604298 0.80 HTR6 (0.61) HTR6ALDH1A1SMN1; SMN2POLBDDX3X
SCHEMBL2446287 0.79 HTR6 (0.56) HTR6ALDH1A1POLBDDX3XKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773289-A Nitrobenzoisothiazole azo compound and application thereof 辽宁庸信达染料化工有限公司 2022-07-22 CN disclosed