Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | DDX3X | O00571 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL399855 | 1.00 | HTR6 (0.61) | HTR6KEAP1ALDH1A1SMN1; SMN2TYRO3 | |
| SCHEMBL698855 | 0.85 | KEAP1 (0.70) | KEAP1ALDH1A1SMN1; SMN2POLBKIF11 | |
| SCHEMBL10138631 | 0.85 | HTR6 (0.57) | HTR6ALDH1A1SMN1; SMN2TYRO3POLB | |
| SCHEMBL8547020 | 0.82 | HTR6 (0.62) | HTR6ALDH1A1POLBDDX3XKDM4E | |
| SCHEMBL11655851 | 0.81 | HTR6 (0.57) | HTR6ALDH1A1SMN1; SMN2POLBDDX3X | |
| SCHEMBL12728616 | 0.80 | HTR6 (0.61) | HTR6ALDH1A1SMN1; SMN2POLBDDX3X | |
| SCHEMBL31604298 | 0.80 | HTR6 (0.61) | HTR6ALDH1A1SMN1; SMN2POLBDDX3X | |
| SCHEMBL16181301 | 0.80 | HTR6 (0.51) | HTR6ALDH1A1SMN1; SMN2TYRO3POLB | |
| SCHEMBL27861796 | 0.80 | HTR6 (0.61) | HTR6ALDH1A1SMN1; SMN2POLBDDX3X | |
| SCHEMBL2446287 | 0.79 | HTR6 (0.56) | HTR6ALDH1A1POLBDDX3XKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773289-A | Nitrobenzoisothiazole azo compound and application thereof | 辽宁庸信达染料化工有限公司 | 2022-07-22 | — | — | CN | disclosed |