Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | DRD1 | P21728 | 5/20 | 0.49 |
| ▸ | DRD4 | P21917 | 5/20 | 0.49 |
| ▸ | DRD5 | P21918 | 5/20 | 0.49 |
| ▸ | DRD3 | P35462 | 5/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 12/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29795303 | 0.81 | HCRTR2 (0.48) | HCRTR2MEN1KMT2A | |
| SCHEMBL29795298 | 0.80 | HTR1A (0.48) | HCRTR2PTGDR2MEN1KMT2A | |
| SCHEMBL6606604 | 0.79 | SMN1; SMN2 (0.54) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL29860512 | 0.78 | ADAM10 (0.47) | HCRTR2 | |
| SCHEMBL29860760 | 0.78 | ADAM10 (0.47) | HCRTR2 | |
| SCHEMBL29666678 | 0.77 | HCRTR2 (0.57) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL29795231 | 0.77 | BRD4 (0.36) | HCRTR2MEN1KMT2A | |
| SCHEMBL30725986 | 0.77 | ADAM10 (0.48) | HCRTR2 | |
| SCHEMBL22444937 | 0.76 | DRD2 (0.60) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL9956909 | 0.75 | DRD2 (0.62) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761412-A | Substituted macrocyclic compounds and related methods of treatment | 阿尔克姆斯有限公司 | 2022-07-15 | — | — | CN | disclosed |