Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29795303 | 0.85 | HCRTR2 (0.48) | BRD4HCRTR2L3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL29860512 | 0.81 | ADAM10 (0.47) | BRD4HCRTR2 | |
| SCHEMBL29860760 | 0.81 | ADAM10 (0.47) | BRD4HCRTR2 | |
| SCHEMBL30725986 | 0.80 | ADAM10 (0.48) | BRD4HCRTR2 | |
| SCHEMBL22978758 | 0.78 | ALDH1A1 (0.47) | L3MBTL1POLBSMN1; SMN2GAAKDM4E | |
| SCHEMBL29795298 | 0.78 | HTR1A (0.48) | HCRTR2SMN1; SMN2NPC1RAB9ANPSR1 | |
| SCHEMBL29795241 | 0.77 | DRD2 (0.49) | HCRTR2MEN1KMT2A | |
| SCHEMBL30725996 | 0.74 | GPR119 (0.47) | HCRTR2L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL23064606 | 0.71 | SMN1; SMN2 (0.48) | BRD4L3MBTL1POLBSMN1; SMN2NPC1 | |
| SCHEMBL548147 | 0.70 | LMNA (0.52) | SMN1; SMN2GAATSHRMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761412-A | Substituted macrocyclic compounds and related methods of treatment | 阿尔克姆斯有限公司 | 2022-07-15 | — | — | CN | disclosed |