SCHEMBL537148

SCHEMBL537148

CC(C)CC(NC(=O)C(N)CCC(=O)O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 8/20 0.64
DPP4 P27487 1/20 0.58
DPP8 Q6V1X1 1/20 0.58
DPP9 Q86TI2 1/20 0.58
ALDH1A1 P00352 2/20 0.51
NAALAD2 Q9Y3Q0 1/20 0.50
LAP3 P28838 3/20 0.49
MEN1 O00255 1/20 0.49
LMNA P02545 1/20 0.49
KMT2A Q03164 1/20 0.49
GRM8 O00222 1/20 0.48
GRM6 O15303 1/20 0.48
GRIN2D O15399 1/20 0.48
GRIN3B O60391 1/20 0.48
GSR P00390 1/20 0.48
CYP1A2 P05177 1/20 0.48
GRIK1 P39086 1/20 0.48
GRM5 P41594 1/20 0.48
GRIA1 P42261 1/20 0.48
GRIA2 P42262 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30676233 1.00 FOLH1 (0.64) FOLH1DPP4DPP8DPP9ALDH1A1
SCHEMBL537147 1.00 FOLH1 (0.64) FOLH1DPP4DPP8DPP9ALDH1A1
SCHEMBL29796607 0.97 FOLH1 (0.60) FOLH1DPP4DPP8DPP9ALDH1A1
SCHEMBL31195712 0.97 FOLH1 (0.60) FOLH1DPP4DPP8DPP9ALDH1A1
SCHEMBL30784907 0.97 FOLH1 (0.60) FOLH1DPP4DPP8DPP9ALDH1A1
Leucine SCHEMBL14126311 0.95 FOLH1 (0.59) FOLH1DPP4DPP8DPP9ALDH1A1
SCHEMBL29400510 0.95 FOLH1 (0.63) FOLH1DPP4DPP8DPP9NAALAD2
Leucine SCHEMBL14126312 0.95 FOLH1 (0.59) FOLH1DPP4DPP8DPP9ALDH1A1
SCHEMBL5329396 0.94 FOLH1 (0.57) FOLH1DPP4DPP8DPP9BACE1
SCHEMBL29441706 0.94 FOLH1 (0.57) FOLH1DPP4DPP8DPP9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118897023-B Method for directly measuring alpha and gamma-glutamyl peptide in skeletal muscle by using LC-MS and isotope dilution assay 中国农业科学院北京畜牧兽医研究所 2025-03-25 CN claimed
US-20250027938-A1 METABOLIC SIGNATURE FOR PREDICTION OF MUCOSAL INFLAMMATION AND MICROBIAL COMPOSITION IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2025-01-23 US claimed
CN-118897023-A Method for directly measuring alpha and gamma-glutamyl peptide in skeletal muscle by using LC-MS and isotope dilution assay 中国农业科学院北京畜牧兽医研究所 2024-11-05 CN claimed
EP-4370919-A1 METABOLIC SIGNATURE FOR PREDICTION OF MUCOSAL INFLAMMATION AND MICROBIAL COMPOSITION Imperial College Innovations Limited (GB) 2024-05-22 EP claimed
WO-2023285832-A1 METABOLIC SIGNATURE FOR PREDICTION OF MUCOSAL INFLAMMATION AND MICROBIAL COMPOSITION IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2023-01-19 WO claimed
EP-3987064-A1 METHOD FOR DIAGNOSING ESTHETIC DEGRADATIONS OF SKIN L'OREAL (FR) 2022-04-27 EP claimed
WO-2020260355-A1 METHOD FOR DIAGNOSING ESTHETIC DEGRADATIONS OF SKIN L'OREAL (FR) 2020-12-30 WO claimed
US-20190120855-A1 Biomarkers for Fatty Liver Disease and Methods Using the Same THE CLEVELAND CLINIC FOUNDATION 2019-04-25 US claimed
US-9977034-B2 Biomarkers for fatty liver disease and methods using the same Meabolon, Inc. (US) 2018-05-22 US claimed
US-20150377910-A1 Biomarkers for Fatty Liver Disease and Methods Using the Same METABOLON, INC. 2015-12-31 US claimed
EP-2546649-B1 Biomarkers for fatty liver disease and methods using the same METABOLON INC (US) 2015-02-25 EP claimed
WO-2013188333-A1 BIOMARKERS RELATED TO NEPHROTOXICITY AND METHODS USING THE SAME METABOLON, INC. (US) 2013-12-19 WO claimed
WO-2013155528-A2 METHODS FOR REDUCING BRAIN INFLAMMATION, INCREASING INSULIN SENSITIVITY, AND REDUCING CERAMIDE LEVELS FASGEN, INC. (US) 2013-10-17 WO claimed
EP-2546649-A2 Biomarkers for fatty liver disease and methods using the same Metabolon Inc. (US) 2013-01-16 EP claimed
EP-2227689-B1 BIOMARKERS FOR FATTY LIVER DISEASE AND METHODS USING THE SAME METABOLON INC (US) 2012-12-26 EP claimed
US-20100279956-A1 Biomarkers For Fatty Liver Disease And Methods Using The Same METABOLON, INC. 2010-11-04 US claimed
CN-122045749-A Method for identifying key flavor substances of rice based on materially group science and machine learning 华中农业大学 2026-05-15 CN disclosed
US-12534439-B2 Xanthohumol derivatives and methods for making and using OREGON STATE UNIVERSITY (US) 2026-01-27 US disclosed
WO-1997031938-A9 OLIGOPEPTIDES FOR DRUG DELIVERY 1997-11-20 WO disclosed
WO-1997031938-A1 OLIGOPEPTIDES FOR DRUG DELIVERY EMISPHERE TECHNOLOGIES, INC. (US) 1997-09-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534439-B2 Xanthohumol derivatives and methods for making and using MT-CO1, MT-CO2, PC FOLH1 3243/4885DPP4 1656/4885DPP8 1136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.