Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21952069 | 1.00 | ALDH1A1 (0.44) | ALDH1A1GAARAB9ALMNAMAPK1 | |
| SCHEMBL31396338 | 0.89 | ALPL (0.43) | ALDH1A1GAALMNAMAPK1NPSR1 | |
| SCHEMBL21952011 | 0.85 | LMNA (0.47) | ALDH1A1GAARAB9ALMNAMAPK1 | |
| SCHEMBL21952098 | 0.81 | MAPT (0.56) | ALDH1A1GAALMNAMAPK1NPSR1 | |
| SCHEMBL29798210 | 0.80 | MAPT (0.47) | ALDH1A1GAARAB9ALMNAMAPK1 | |
| SCHEMBL31396222 | 0.74 | ALPL (0.47) | ALDH1A1GAALMNAMAPK1NPSR1 | |
| SCHEMBL21952094 | 0.72 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPK1NPSR1TSHR | |
| SCHEMBL31396379 | 0.72 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPK1NPSR1TSHR | |
| SCHEMBL21952071 | 0.71 | TSHR (0.52) | ALDH1A1GAALMNAMAPK1MAPT | |
| SCHEMBL30278740 | 0.71 | TSHR (0.52) | ALDH1A1GAALMNAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4149461-A1 | UBIQUITIN-LIGASE INHIBITORS FOR THE TREATMENT OF CANCER | Fundación Profesor Novoa Santos (ES) | 2023-03-22 | — | — | EP | disclosed |
| WO-2021229035-A9 | UBIQUITIN-LIGASE INHIBITORS FOR THE TREATMENT OF CANCER | FUNDACIÓN PROFESOR NOVOA SANTOS (ES) | 2022-09-09 | — | — | WO | disclosed |