SCHEMBL2979868

SCHEMBL2979868

CNN(C(=O)O)C(CC=O)C1CCN(CCc2cccc(Cl)c2)CC1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 6/20 0.43
UBE2M P61081 1/20 0.43
DCUN1D1 Q96GG9 1/20 0.43
CCR5 P51681 1/20 0.42
CARM1 Q86X55 2/20 0.42
PRMT6 Q96LA8 2/20 0.42
OPRD1 P41143 1/20 0.41
SIGMAR1 Q99720 2/20 0.40
HTR1A P08908 1/20 0.39
SLC6A4 P31645 1/20 0.39
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2970397 0.85 DRD4 (0.45) OPRM1SIGMAR1HTR1ASLC6A4
SCHEMBL2982102 0.82 OPRM1 (0.40) OPRM1OPRD1SIGMAR1
SCHEMBL2970171 0.81 TEAD1 (0.45) SIGMAR1
Hydrochloric Acid SCHEMBL2971262 0.81 TEAD1 (0.44) SIGMAR1
SCHEMBL2981934 0.80 OPRM1 (0.44) OPRM1OPRD1SIGMAR1
SCHEMBL2983978 0.79 MEN1 (0.51) SIGMAR1HTR1A
SCHEMBL2980738 0.78 UBE2M (0.34) UBE2MDCUN1D1CCR5SLC6A4
SCHEMBL2970365 0.78 BCHE (0.45)
SCHEMBL2982137 0.77 POLB (0.48) SIGMAR1
SCHEMBL2980439 0.76 KCNA3 (0.48) OPRM1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7781590-B2 Piperidinylalkylcarbamate derivatives, methods for their preparation and the therapeutic use thereof as fatty acid amido hydrolase enzyme inhibitors SANOFI-AVENTIS (FR) 2010-08-24 US disclosed
US-20070021403-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS SANOFI-AVENTIS (FR) 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070021403-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS FAAH, FAAH2, CNR2 OPRM1 627/4885UBE2M 3836/4885DCUN1D1 4751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.