Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 9/20 | 0.46 |
| ▸ | MGLL | Q99685 | 6/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29799500 | 0.77 | ABHD6 (0.49) | ABHD6MGLLFAAH | |
| SCHEMBL29799563 | 0.74 | PPARG (0.41) | PPARGPPARALTA4HMCL1LMNA | |
| SCHEMBL29799628 | 0.73 | ABHD6 (0.46) | ABHD6MGLLFAAH | |
| SCHEMBL26922545 | 0.71 | SMN1; SMN2 (0.51) | PPARGPPARALTA4HSMN1; SMN2GAA | |
| SCHEMBL31680936 | 0.69 | SMN1; SMN2 (0.56) | SMN1; SMN2PRMT5GAA | |
| SCHEMBL24763408 | 0.69 | KDM1A (0.47) | LMNASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL24762050 | 0.69 | LMNA (0.41) | PPARGPPARALTA4HMCL1LMNA | |
| SCHEMBL24762619 | 0.68 | HTR2A (0.45) | MCL1LMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL23250071 | 0.68 | ABHD6 (0.39) | ABHD6MGLLSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL24762182 | 0.68 | PKM (0.55) | LMNANPC1ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240327351-A1 | AMIDE AND ETHER SUBSTITUTED N-(1H-INDOL-7-YL)BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES INC (US) | 2024-10-03 | — | — | US | disclosed |
| WO-2022173805-A1 | AMIDE AND ETHER SUBSTITUTED N-(1H-INDOL-7-YL)BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327351-A1 | AMIDE AND ETHER SUBSTITUTED N-(1H-INDOL-7-YL)BENZENESULFONAMIDES AND USES THEREOF | PACSIN2, AADAC, DNPEP | ABHD6 743/4885MGLL 2947/4885PPARG 1134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.