SCHEMBL298008

SCHEMBL298008

CCOC(=O)C1(NC(=O)OC(C)(C)C)CC(O)C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.38
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 2/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HTT P42858 1/20 0.35
CA12 O43570 2/20 0.34
CA14 Q9ULX7 2/20 0.34
CA1 P00915 1/20 0.34
CA7 P43166 1/20 0.34
LMNA P02545 1/20 0.33
GHSR Q92847 1/20 0.33
CTSL P07711 1/20 0.33
HCRTR2 O43614 1/20 0.33
CPB2 Q96IY4 1/20 0.32
CACNA1H O95180 1/20 0.32
HDAC4 P56524 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10040060 1.00 KMT2A (0.38) KMT2AALDH1A1MEN1TSHRMAPK1
SCHEMBL13525930 1.00 KMT2A (0.38) KMT2AALDH1A1MEN1TSHRMAPK1
SCHEMBL25492214 0.89 KMT2A (0.38) KMT2AALDH1A1MEN1TSHRMAPK1
SCHEMBL4434237 0.89 KMT2A (0.38) KMT2AALDH1A1MEN1TSHRMAPK1
SCHEMBL15826780 0.88 KMT2A (0.38) KMT2AALDH1A1MEN1TSHRMAPK1
SCHEMBL15306516 0.88 KMT2A (0.38) KMT2AALDH1A1MEN1TSHRMAPK1
SCHEMBL6886075 0.88 KMT2A (0.38) KMT2AALDH1A1MEN1TSHRMAPK1
SCHEMBL15257504 0.88 KMT2A (0.38) KMT2AALDH1A1MEN1TSHRMAPK1
SCHEMBL12173239 0.88 KMT2A (0.38) KMT2AALDH1A1MEN1TSHRMAPK1
SCHEMBL2362032 0.88 KMT2A (0.38) KMT2AALDH1A1MEN1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823001-A Urea compounds antagonizing LPA1 receptor 大正制药株式会社 2025-04-15 CN disclosed
CN-114206832-B Urea compounds antagonizing LPA1 receptor 大正制药株式会社 2025-04-04 CN disclosed
EP-3354639-B1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDIPHYSICS CO LTD (JP) 2024-02-21 EP disclosed
EP-3530648-B1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDIPHYSICS CO LTD (JP) 2023-11-08 EP disclosed
CN-114206832-A Urea compounds antagonizing LPA1 receptor 大正制药株式会社 2022-03-18 CN disclosed
EP-3950673-A1 INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF Inspirna, Inc. (US) 2022-02-09 EP disclosed
US-20210386873-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDIPHYSICS CO LTD (JP) 2021-12-16 US disclosed
US-11083804-B2 Precursor compound of radioactive halogen-labeled organic compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2021-08-10 US disclosed
US-10953112-B2 Precursor compound of radioactive halogen-labeled organic compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2021-03-23 US disclosed
US-20200282082-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2020-09-10 US disclosed
US-7897811-B2 Process for production of radioactive fluorine-labeled organic compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2011-03-01 US disclosed
US-20100261931-A1 PROCESS FOR PRODUCTION OF RADIOACTIVE-FLUORINE-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2010-10-14 US disclosed
EP-2230229-A1 PROCESS FOR PRODUCTION OF RADIOACTIVE-FLUORINE-LABELED ORGANIC COMPOUND Nihon Medi-Physics Co., Ltd. (JP) 2010-09-22 EP disclosed
WO-2010070615-A1 CYSTEINE PROTEASE INHIBITORS MEDIVIR UK LTD (GB) 2010-06-24 WO disclosed
US-20100016626-A1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2010-01-21 US disclosed
EP-2128130-A1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND Nihon Medi-Physics Co., Ltd. (JP) 2009-12-02 EP disclosed
US-20090198085-A1 Process for Production of Radioactive Fluorine-Labeled Organic Compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2009-08-06 US disclosed
EP-2017258-A1 PROCESS FOR PRODUCTION OF RADIOACTIVE FLUORINE-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2009-01-21 EP disclosed
US-20080281121-A1 Precursor Compound of Radioactive Halogen-Labeled Organic Compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2008-11-13 US disclosed
EP-1978015-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2008-10-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11083804-B2 Precursor compound of radioactive halogen-labeled organic compound BCAT2, SLCO2B1, ORC3 KMT2A 3576/4885ALDH1A1 2188/4885MEN1 3670/4885
US-20210386873-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND BCAT2, SLCO2B1, ORC3 KMT2A 3576/4885ALDH1A1 2188/4885MEN1 3670/4885
US-20100016626-A1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND FUS, SLC43A1, PFAS KMT2A 3174/4885ALDH1A1 3514/4885MEN1 1351/4885
US-20090198085-A1 Process for Production of Radioactive Fluorine-Labeled Organic Compound FOSB, AFF1, SLCO4C1 KMT2A 1919/4885ALDH1A1 1287/4885MEN1 797/4885
US-20100261931-A1 PROCESS FOR PRODUCTION OF RADIOACTIVE-FLUORINE-LABELED ORGANIC COMPOUND AFF1, SLCO4C1, SLCO2A1 KMT2A 2150/4885ALDH1A1 673/4885MEN1 793/4885
US-20080281121-A1 Precursor Compound of Radioactive Halogen-Labeled Organic Compound BCAT2, SLCO2B1, ORC3 KMT2A 3576/4885ALDH1A1 2188/4885MEN1 3670/4885
US-20200282082-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND BCAT2, SLCO2B1, ORC3 KMT2A 3576/4885ALDH1A1 2188/4885MEN1 3670/4885
US-10953112-B2 Precursor compound of radioactive halogen-labeled organic compound BCAT2, SLCO2B1, ORC3 KMT2A 3576/4885ALDH1A1 2188/4885MEN1 3670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.