Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.38 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PEPD | P12955 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27712099 | 0.93 | PREP (0.44) | ACEDPP4PREPFAPREN | |
| SCHEMBL27712097 | 0.93 | PREP (0.44) | ACEDPP4PREPFAPREN | |
| SCHEMBL30501947 | 0.92 | OPRM1 (0.41) | ACEXIAPCAPN1OPRM1OPRD1 | |
| SCHEMBL30853261 | 0.85 | ACE (0.42) | ACEXIAPDPP4PREPFAP | |
| SCHEMBL30575171 | 0.85 | PREP (0.42) | ACEDPP4PREPFAPREN | |
| SCHEMBL29867437 | 0.84 | PREP (0.44) | ACEDPP4PREPFAPREN | |
| SCHEMBL31564810 | 0.84 | FAP (0.44) | ACEXIAPDPP4PREPFAP | |
| SCHEMBL29409431 | 0.84 | DPP4 (0.41) | ACEDPP4PREPFAPCAPN1 | |
| SCHEMBL31206805 | 0.83 | REN (0.43) | ACECALCRLRENKDM4EF2 | |
| SCHEMBL29409434 | 0.83 | NAA50 (0.45) | ACEDPP4PREPFAPPSMB9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422799-B | Docetaxel liver cancer-resisting targeted prodrug and medicinal application thereof | 复旦大学 | 2022-07-29 | — | — | CN | disclosed |