Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 2/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24976786 | 1.00 | PIK3CA (0.48) | PIK3CAKMT2ACYP2C9NAMPTHPGDS | |
| SCHEMBL29801063 | 0.83 | THRB (0.57) | PIK3CAKMT2ACYP2C9ALDH1A1HPGD | |
| SCHEMBL17888306 | 0.82 | PIK3CA (0.55) | PIK3CAKMT2ACYP2C9NAMPTALDH1A1 | |
| SCHEMBL17886678 | 0.79 | LMNA (0.59) | PIK3CAKMT2ANAMPTALDH1A1HDAC6 | |
| SCHEMBL21077877 | 0.78 | RAB9A (0.52) | PIK3CAKMT2ACYP2C9NAMPTALDH1A1 | |
| SCHEMBL28844093 | 0.77 | P2RX7 (0.50) | PIK3CAKMT2ACYP2C9NAMPTMAPK8 | |
| SCHEMBL29801234 | 0.76 | MEN1 (0.64) | KMT2ANAMPTALDH1A1HPGDHDAC1 | |
| SCHEMBL24685295 | 0.76 | MEN1 (0.64) | KMT2ANAMPTALDH1A1HPGDHDAC1 | |
| SCHEMBL13731868 | 0.76 | CYP2C9 (0.59) | PIK3CAKMT2ACYP2C9NAMPTALDH1A1 | |
| SCHEMBL30421108 | 0.74 | CYP2C9 (0.54) | PIK3CAKMT2ACYP2C9NAMPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930509-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-114929672-B | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2025-01-21 | — | — | CN | disclosed |
| EP-4055008-A1 | CANCER TREATMENTS TARGETING CANCER STEM CELLS | Remedy Plan, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |
| CN-114929672-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2022-08-19 | — | — | CN | disclosed |