Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.42 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.41 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1552453 | 0.92 | OPRM1 (0.43) | OPRM1OPRK1EPHA2NMUR2NMUR1 | |
| SCHEMBL1552457 | 0.92 | OPRM1 (0.43) | OPRM1OPRK1EPHA2NMUR2NMUR1 | |
| SCHEMBL31511421 | 0.92 | OPRM1 (0.42) | OPRM1OPRK1EPHA2NMUR2NMUR1 | |
| SCHEMBL29723642 | 0.90 | OPRM1 (0.51) | OPRM1OPRK1EPHA2 | |
| SCHEMBL31603941 | 0.89 | APLNR (0.45) | OPRM1OPRK1NMUR2NMUR1 | |
| SCHEMBL29802094 | 0.89 | OPRM1 (0.45) | OPRM1OPRK1EPHA2NMUR2NMUR1 | |
| SCHEMBL21027181 | 0.89 | NRP1 (0.45) | OPRM1OPRK1EPHA2NMUR2NMUR1 | |
| SCHEMBL11231534 | 0.88 | OPRM1 (0.46) | OPRM1OPRK1NMUR2NMUR1ACE | |
| SCHEMBL11231542 | 0.88 | OPRM1 (0.46) | OPRM1OPRK1NMUR2NMUR1ACE | |
| SCHEMBL21026612 | 0.88 | F2 (0.41) | OPRM1OPRK1EPHA2NMUR2NMUR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306534-A1 | MULTIFUNCTIONAL POLYPEPTIDE AND APPLICATION THEREOF IN FIELD OF MEDICINES | Wuhan Innerse Pharmaceutical Inc. (CN) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022188878-A1 | MULTIFUNCTIONAL POLYPEPTIDE AND APPLICATION THEREOF IN FIELD OF MEDICINES | 武汉英纳氏药业有限公司 | 2022-09-15 | — | — | WO | disclosed |