Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 11/20 | 0.53 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.53 |
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
| ▸ | GNPAT | O15228 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534663 | 0.94 | GNPAT (0.54) | BACE1BACE2CTSDGNPATENPEP | |
| SCHEMBL31378167 | 0.92 | GNPAT (0.48) | BACE1BACE2CTSDGNPATFOLH1 | |
| SCHEMBL14008770 | 0.89 | ALDH1A1 (0.63) | GNPATFOLH1ALDH1A1 | |
| SCHEMBL31634368 | 0.87 | KDM4E (0.51) | BACE1BACE2CTSDGNPATFOLH1 | |
| SCHEMBL29802264 | 0.86 | TASP1 (0.51) | BACE1BACE2CTSD | |
| SCHEMBL7166591 | 0.86 | GNPAT (0.48) | BACE1BACE2GNPATENPEP | |
| SCHEMBL22310788 | 0.85 | GNPAT (0.47) | BACE1BACE2CTSDGNPATENPEP | |
| SCHEMBL15765356 | 0.85 | ALDH1A1 (0.69) | GNPATFOLH1ALDH1A1 | |
| SCHEMBL29112234 | 0.84 | ALDH1A1 (0.68) | GNPATFOLH1ALDH1A1 | |
| SCHEMBL29808461 | 0.84 | ALDH1A1 (0.68) | GNPATFOLH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12133720-B2 | Methods and compositions for restoring homeostatic capacity of a subject | Palo Alto Investors LP (US) | 2024-11-05 | — | — | US | disclosed |
| WO-2022190064-A1 | METHODS FOR IDENTIFYING SUBJECTS WITH BETACORONAVIRUS INFECTIONS WHO ARE AT RISK OF ACUTE RESPIRATORY SYNDROME AND METHODS FOR THE TREATMENT OF SAME | VEXO PHARMACEUTICALS DMCC (AE) | 2022-09-15 | — | — | WO | disclosed |