SCHEMBL29802264

SCHEMBL29802264

CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@H](C=O)CC(=O)O)C(C)C

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TASP1 Q9H6P5 1/20 0.51
▸ BACE1 P56817 12/20 0.46
▸ BACE2 Q9Y5Z0 4/20 0.46
▸ CASP1 P29466 3/20 0.45
▸ CASP3 P42574 2/20 0.45
▸ CASP9 P55211 2/20 0.45
▸ CASP7 P55210 1/20 0.45
▸ CTSD P07339 2/20 0.43
▸ PTPN1 P18031 1/20 0.41
▸ FURIN P09958 1/20 0.40
▸ PCSK6 P29122 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13194679 0.93 CASP1 (0.50) TASP1BACE1BACE2CASP1CASP3
SCHEMBL29310042 0.93 CASP1 (0.50) TASP1BACE1BACE2CASP1CASP3
SCHEMBL1674857 0.93 CASP1 (0.50) TASP1BACE1BACE2CASP1CASP3
SCHEMBL4100803 0.93 CASP1 (0.50) TASP1BACE1BACE2CASP1CASP3
SCHEMBL10068454 0.93 CASP1 (0.47) TASP1BACE1BACE2CASP1CASP3
SCHEMBL29946268 0.93 TASP1 (0.51) TASP1BACE1BACE2CASP1PTPN1
SCHEMBL29664764 0.88 TASP1 (0.56) TASP1BACE1BACE2CASP1CASP3
SCHEMBL20257263 0.87 TASP1 (0.53) TASP1CASP1CASP3CASP9CASP7
SCHEMBL20257260 0.87 TASP1 (0.53) TASP1CASP1CASP3CASP9CASP7
SCHEMBL29802241 0.86 BACE1 (0.53) BACE1BACE2CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-05-08 — — US disclosed
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-04-17 — — US disclosed
US-12139744-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2024-11-12 — — US disclosed
US-12133720-B2 Methods and compositions for restoring homeostatic capacity of a subject Palo Alto Investors LP (US) 2024-11-05 — — US disclosed
US-12110533-B2 Stabilisation and isolation of extracellular nucleic acids QIAGEN GMBH (DE) 2024-10-08 — — US disclosed
US-20240287574-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS QIAGEN GMBH (DE) 2024-08-29 — — US disclosed
EP-4397770-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PreAnalytiX GmbH (CH) 2024-07-10 — — EP disclosed
EP-3401406-B1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PREANALYTIX GMBH (CH) 2023-11-29 — — EP disclosed
US-11525155-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2022-12-13 — — US disclosed
US-20220364149-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2022-11-17 — — US disclosed
WO-2022190064-A1 METHODS FOR IDENTIFYING SUBJECTS WITH BETACORONAVIRUS INFECTIONS WHO ARE AT RISK OF ACUTE RESPIRATORY SYNDROME AND METHODS FOR THE TREATMENT OF SAME VEXO PHARMACEUTICALS DMCC (AE) 2022-09-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 TASP1 4313/4885BACE1 2824/4885BACE2 1807/4885
US-12139744-B2 Stabilisation of biological samples RNASE1, RNASEH1, EWSR1 TASP1 4313/4885BACE1 2824/4885BACE2 1807/4885
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 TASP1 4313/4885BACE1 2824/4885BACE2 1807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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