Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23093438 | 1.00 | PTGS2 (0.48) | PTGS2HDAC6PTGS1SCDGRM2 | |
| SCHEMBL19243065 | 0.81 | THRB (0.54) | PTGS2HDAC6 | |
| SCHEMBL19237521 | 0.80 | HDAC6 (0.44) | PTGS2HDAC6PTGS1 | |
| SCHEMBL15730486 | 0.80 | PTGS2 (0.48) | PTGS2HDAC6PTGS1 | |
| SCHEMBL29802549 | 0.79 | ASIC3 (0.56) | PTGS2HDAC6 | |
| SCHEMBL23093295 | 0.79 | PTGS2 (0.49) | PTGS2HDAC6PTGS1 | |
| SCHEMBL29802375 | 0.79 | PTGS2 (0.49) | PTGS2HDAC6PTGS1 | |
| SCHEMBL23093471 | 0.79 | ASIC3 (0.56) | PTGS2HDAC6 | |
| SCHEMBL23093224 | 0.79 | PIK3CD (0.43) | — | |
| SCHEMBL29802465 | 0.79 | PIK3CD (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4027993-A1 | CYCLOOXYGENASE-2 INHIBITORS AND USES THEREOF | The Broad Institute Inc. (US) | 2022-07-20 | — | — | EP | disclosed |