Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.35 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.35 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3110288 | 0.81 | HTR7 (0.46) | HTTF9F10MAPK14HPGD | |
| SCHEMBL5250773 | 0.78 | TDP1 (0.42) | HTTF9F10NPC1RAB9A | |
| SCHEMBL7530934 | 0.75 | CYP2D6 (0.45) | HTTMAPK14NPC1HPGDGABRA1 | |
| SCHEMBL8551819 | 0.73 | CYP11B1 (0.41) | HDAC1HDAC6HDAC5DRD4CYP11B1 | |
| SCHEMBL8605948 | 0.73 | POLB (0.40) | HTTMAPK14SMN1; SMN2ALDH1A1 | |
| SCHEMBL29518247 | 0.73 | GRM5 (0.46) | HDAC1HDAC6HDAC5CYP11B1CYP11B2 | |
| SCHEMBL229009 | 0.73 | GRM5 (0.46) | HDAC1HDAC6HDAC5CYP11B1CYP11B2 | |
| SCHEMBL23110546 | 0.71 | MAPK14 (0.43) | HTTMAPK14NPC1RAB9AHPGD | |
| SCHEMBL3111982 | 0.71 | ADRB1 (0.46) | HTTHPGDCYP3A4ALDH1A1LMNA | |
| SCHEMBL8966043 | 0.71 | BCAT2 (0.41) | HTTF9F10HPGDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247633-B2 | Pyrimidine compounds and their use | BIOVITRUM AB (SE) | 2007-07-24 | — | — | US | disclosed |
| US-20040014767-A1 | Novel compounds and their use | BIOVITRUM AB, A SWEDISH CORPORATION | 2004-01-22 | — | — | US | disclosed |
| EP-1335907-A1 | PIPERAZINYLPYRAZINE COMPOUNDS AS AGONIST OR ANTAGONIST OF SEROTONIN 5HT-2 RECEPTOR | BIOVITRUM AB (SE) | 2003-08-20 | — | — | EP | disclosed |
| US-6593330-B2 | Central nervous system disorders; antiserotonine agents | BIOVITRUM (SE) | 2003-07-15 | — | — | US | disclosed |
| US-20020147200-A1 | Novel compounds and their use | PROXIMAGEN NEUROSCIENCE PLC (GB) | 2002-10-10 | — | — | US | disclosed |
| WO-2002040456-A1 | PIPERAZINYLPYRAZINE COMPOUNDS AS AGONIST OR ANTAGONIST OF SEROTONIN 5HT-2 RECEPTOR | BIOVITRUM AB (SE) | 2002-05-23 | — | — | WO | disclosed |
| EP-0693490-B1 | 2-Phenoxy-6-thienylmethyloxypyridine derivative, process for producing the same, and herbicidal composition | KUREHA CHEMICAL IND CO LTD (JP) | 1998-09-09 | — | — | EP | disclosed |
| US-5624942-A | 2-phenoxy-6-thienylmethyloxypyridine derivative and herbicidal composition containing same | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0693490-A1 | 2-Phenoxy-6-thienylmethyloxypyridine derivative, process for producing the same, and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147200-A1 | Novel compounds and their use | BRIX1, UGT1A1, NR5A1 | HDAC1 666/4885HDAC6 748/4885HDAC5 1388/4885 |
| US-20040014767-A1 | Novel compounds and their use | BRIX1, UGT1A1, NR5A1 | HDAC1 666/4885HDAC6 748/4885HDAC5 1388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.