Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.41 |
| ▸ | FDPS | P14324 | 9/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5680375 | 1.00 | TSHR (0.47) | TSHRTHRBGGPS1FDPSSMPD1 | |
| Hydrochloric Acid SCHEMBL28645411 | 0.95 | TSHR (0.42) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL30525779 | 0.84 | OPRM1 (0.38) | TSHRTHRBFDPS | |
| Ammonia Solution, Strong SCHEMBL31070822 | 0.84 | FAAH (0.48) | — | |
| SCHEMBL24926430 | 0.83 | CES2 (0.45) | TSHRTHRBGGPS1FDPSCES2 | |
| SCHEMBL20047649 | 0.83 | CES2 (0.45) | TSHRTHRBGGPS1FDPSCES2 | |
| SCHEMBL21536059 | 0.81 | CES2 (0.43) | TSHRTHRBGGPS1FDPSCES2 | |
| SCHEMBL20419702 | 0.78 | TSHR (0.42) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL18577823 | 0.78 | SMPD1 (0.45) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL21180176 | 0.78 | SMPD1 (0.45) | TSHRTHRBGGPS1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929748-A | anti-B7-H3 monoclonal antibodies and methods of use thereof | 得克萨斯州大学系统董事会 | 2022-08-19 | — | — | CN | disclosed |