Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CCR9 | P51686 | 2/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.45 |
| ▸ | CNR2 | P34972 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3005616 | 0.92 | CCR2 (0.62) | CCR2MEN1KMT2AKDM4EPTGDR2 | |
| SCHEMBL2539595 | 0.83 | NOD2 (0.55) | MEN1KMT2AKDM4EPTGDR2CYP1A2 | |
| SCHEMBL2815078 | 0.82 | ATM (0.62) | CCR2MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL297540 | 0.81 | CCR2 (0.46) | CCR2MEN1KMT2ACCR9GPR35 | |
| SCHEMBL3757847 | 0.80 | GPR35 (0.48) | CCR2MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL1100863 | 0.79 | CCR2 (0.61) | CCR2MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL3009191 | 0.79 | GPR35 (0.44) | CCR2MEN1KMT2AKDM4EPTGDR2 | |
| SCHEMBL4395300 | 0.78 | CCR2 (0.52) | CCR2MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL3259343 | 0.78 | FDPS (0.48) | CCR2MEN1KMT2AKDM4EPTGDR2 | |
| SCHEMBL298863 | 0.78 | CCR9 (0.51) | CCR2MEN1KMT2APTGDR2CCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2106401-B1 | DERIVATIVES OF PYRROLOPYRIDINE-2-CARBOXAMIDS, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF | SANOFI SA (FR) | 2012-03-14 | — | — | EP | disclosed |