Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23521941 | 1.00 | NPC1 (0.56) | NPC1MEN1HCRTR1KMT2APOLB | |
| SCHEMBL28687576 | 0.85 | ROCK2 (0.54) | KMT2ALMNAHDAC1MMP13MAPK1 | |
| SCHEMBL30592138 | 0.84 | MMP13 (0.60) | KMT2APOLBLMNAMAOBMMP13 | |
| SCHEMBL23521923 | 0.84 | MMP13 (0.60) | KMT2APOLBLMNAMAOBMMP13 | |
| SCHEMBL29808056 | 0.83 | CYP2C19 (0.58) | MEN1KMT2APOLBLMNAMAPK1 | |
| SCHEMBL23521747 | 0.83 | CYP2C19 (0.58) | MEN1KMT2APOLBLMNAMAPK1 | |
| SCHEMBL23521924 | 0.83 | KMT2A (0.55) | KMT2ALMNAHDAC2HDAC6MMP13 | |
| SCHEMBL29808051 | 0.83 | KMT2A (0.55) | KMT2ALMNAHDAC2HDAC6MMP13 | |
| SCHEMBL23521925 | 0.83 | TSHR (0.51) | MEN1KMT2ALMNAAPEX1HDAC1 | |
| SCHEMBL29807696 | 0.83 | TSHR (0.51) | MEN1KMT2ALMNAAPEX1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3838901-B1 | COMPOUND FOR TREATMENT OF RABIES AND METHOD FOR TREATMENT OF RABIES | IRIMAJIRI THERAPEUTICS INC (JP) | 2023-09-27 | — | — | EP | disclosed |
| CN-115052661-A | Compound and drug using the same | 株式会社大分大学先端医学研究所 | 2022-09-13 | — | — | CN | disclosed |
| CN-112839944-B | Compounds and methods for treating rabies | 株式会社大分大学先端医学研究所 | 2022-08-05 | — | — | CN | disclosed |