Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DDT | P30046 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23521923 | 1.00 | MMP13 (0.60) | MMP13KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7015936 | 0.88 | MMP13 (0.68) | MMP13KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28687576 | 0.85 | ROCK2 (0.54) | MMP13KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL29819690 | 0.85 | KMT2A (0.61) | MMP13KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL23521860 | 0.85 | KMT2A (0.61) | MMP13KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL29807934 | 0.84 | NPC1 (0.56) | MMP13MAOBPOLBKMT2ALMNA | |
| SCHEMBL23521941 | 0.84 | NPC1 (0.56) | MMP13MAOBPOLBKMT2ALMNA | |
| SCHEMBL23521924 | 0.83 | KMT2A (0.55) | MMP13ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL29808051 | 0.83 | KMT2A (0.55) | MMP13ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL29537243 | 0.77 | SMN1; SMN2 (0.57) | MMP13ALDH1A1HSD17B10POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3838901-B1 | COMPOUND FOR TREATMENT OF RABIES AND METHOD FOR TREATMENT OF RABIES | IRIMAJIRI THERAPEUTICS INC (JP) | 2023-09-27 | — | — | EP | disclosed |