Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | CKS1B | P61024 | 2/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13977548 | 0.81 | TDP1 (0.52) | TDP1LMNAMAPTALDH1A1HTT | |
| SCHEMBL6268320 | 0.81 | SLC40A1 (0.49) | TDP1LMNAMAPTALDH1A1HTT | |
| SCHEMBL3263766 | 0.79 | METAP2 (0.76) | TDP1LMNAMAPTALDH1A1HTT | |
| SCHEMBL27862896 | 0.76 | TDP1 (0.48) | TDP1LMNAMAPTALDH1A1HTT | |
| SCHEMBL18263184 | 0.76 | ALDH1A1 (0.51) | LMNAMAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL18318080 | 0.75 | PDE4A (0.45) | TDP1LMNAMAPTALDH1A1HTT | |
| SCHEMBL18419283 | 0.74 | METAP2 (0.69) | TDP1LMNAMAPTALDH1A1HTT | |
| SCHEMBL14820518 | 0.74 | MEN1 (0.50) | LMNAMAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8881578 | 0.73 | KMT2A (0.54) | TDP1LMNAMAPTALDH1A1HTT | |
| SCHEMBL4539236 | 0.73 | LMNA (0.52) | TDP1LMNAMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781589-B2 | Quantitative method of determining beryllium or a compound thereof in a sample | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2010-08-24 | — | — | US | disclosed |
| US-20070141715-A1 | Quantitative method of determining beryllium or a compound thereof in a sample | LOS ALAMOS NATIONAL SECURITY, LLC | 2007-06-21 | — | — | US | disclosed |
| US-7129093-B2 | Quantitative method of determining beryllium or a compound thereof in a sample | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2006-10-31 | — | — | US | disclosed |
| US-20050221498-A1 | Quantitative method of determining beryllium or a compound thereof in a sample | LOS ALAMOS NATIONAL SECURITY, LLC | 2005-10-06 | — | — | US | disclosed |