Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 6/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | SORD | Q00796 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2984808 | 0.84 | ALOX5 (0.48) | MLYCDCA12CA9ALOX5ALDH2 | |
| SCHEMBL5005112 | 0.84 | ALOX5 (0.48) | MLYCDCA12CA9ALOX5ALDH2 | |
| SCHEMBL2979651 | 0.82 | MLYCD (0.49) | MLYCDKCNA3CA12CA9ALOX5 | |
| SCHEMBL2991731 | 0.80 | MLYCD (0.69) | MLYCDKCNA3CA12CA9ALOX5 | |
| SCHEMBL2986642 | 0.75 | ALOX5 (0.51) | MLYCDCA12CA9ALOX5KDM4E | |
| SCHEMBL2986061 | 0.73 | ALOX5 (0.41) | MLYCDCA12CA9ALOX5KDM4E | |
| SCHEMBL2985984 | 0.71 | ALOX5 (0.39) | MLYCDCA12CA9ALOX5KDM4E | |
| SCHEMBL2985671 | 0.69 | MLYCD (0.69) | MLYCDCA12CA9ALOX5KDM4E | |
| SCHEMBL2983754 | 0.69 | ALOX5 (0.57) | MLYCDCA12CA9ALOX5KDM4E | |
| SCHEMBL2975269 | 0.69 | MLYCD (0.66) | MLYCDCA12CA9ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137371-A1 | Novel Pharmaceutical Compounds | MERCK FROSST CANADA LTD. (CA) | 2010-06-03 | — | — | US | disclosed |
| US-7439260-B2 | 7-(1,3-thiazol-2-YL)thio-coumarin derivatives and their use as leukotriene biosynthesis inhibitors | MERCK FORSST CANADA & CO. (CA) | 2008-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137371-A1 | Novel Pharmaceutical Compounds | LTC4S, LTA4H, LTB4R2 | MLYCD 2597/4885KCNA3 3692/4885CA12 3849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.