Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20633529 | 1.00 | LRRK2 (0.35) | LRRK2CNR2S1PR1RORCKCNH2 | |
| SCHEMBL20633516 | 0.90 | LRRK2 (0.39) | LRRK2CNR2S1PR1RORCKCNH2 | |
| SCHEMBL17832756 | 0.88 | MAPT (0.32) | CNR2RORC | |
| SCHEMBL17832754 | 0.87 | KCNH2 (0.35) | CNR2KCNH2 | |
| SCHEMBL31561431 | 0.85 | S1PR1 (0.35) | LRRK2CNR2S1PR1RORCKCNH2 | |
| SCHEMBL20632976 | 0.83 | LRRK2 (0.35) | LRRK2CNR2S1PR1RORCKCNH2 | |
| SCHEMBL30958306 | 0.83 | PTGS2 (0.33) | LRRK2CNR2S1PR1RORCKCNH2 | |
| SCHEMBL17422452 | 0.83 | PTGS2 (0.33) | LRRK2CNR2S1PR1RORCKCNH2 | |
| SCHEMBL19684513 | 0.83 | LRRK2 (0.33) | LRRK2CNR2S1PR1RORC | |
| SCHEMBL20633539 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649118-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2024-08-28 | — | — | EP | disclosed |
| CN-110891949-B | Pesticidally active heterocyclic derivatives with sulfur containing substituents | 先正达参股股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| US-11399542-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2022-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11399542-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | DDT, CHRM1, ACHE | LRRK2 203/4885CNR2 786/4885S1PR1 1577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.